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La calcificación coronaria detectada por fluoroscopia es capaz de predecir la mortalidad a largo plazo;
Fluoroscopic Detection of Coronary Artery Calcification may Predict Long-Term Mortality

Creators:Caccavo, Alberto; CLINICA CORONEL SUÁREZ, Brodsky, Rubén L., Rolandi, Florencia, Caccavo, Francisco
2014-08-15

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Descripción

OBJETIVOS:  La calcificación coronaria (CC) es un marcador de aterosclerosis coronaria. La fluoroscopía es un método accesible de detectar (CC). Se evaluó si la presencia de (CC) por fluoroscopía es predictor independiente de mortalidad global y cardiovascular a largo plazo. MATERIAL Y METODOS: Se estudió una cohorte prospectiva de personas ≥45 años sin enfermedad cardiovascular conocida a quienes se les realizó una fluoroscopía identificando (CC). Se realizó seguimiento a largo plazo y se estudió con un modelo de regresión logística múltiple el efecto independiente de la calcificación como predictor de muerte. RESULTADOS: Se incluyeron 857 individuos. El seguimiento se completó en el 98.7% de los casos con un promedio de 14.4 ± 4.3 años (rango: 34 días a 20.8 años). Edad promedio al ingreso:  61.3 ± 9.7 años, hipertensos (88.9%) 19.6 % con colesterol elevado, 1.8% diabéticos y 52.7% hombres. Se detectó (CC) en 264 (32%). La presencia de (CC) se asoció con edad, sexo masculino y colesterol alto. La mortalidad a largo plazo global fue 28.3% y la cardiovascular 14.9%. La presencia de (CC) resultó ser un predictor independiente de mortalidad global (HR 1.6, IC 95%: 1.2 - 2.0, P=0.002) y cardiovascular (HR 2.5, IC 95%: 1.6 - 3.9, P=0.002). La mortalidad global sin calcificación fue 1.35 cada 100 ptes./año  y con calcificación  3.39 cada 100 ptes./año P(log Rank test) &lt; 0.0001 . CONCLUSIONES: La detección de calcificación coronaria por fluoroscopía, es capaz de predecir de manera independiente mortalidad global y cardiovascular en una población sin enfermedad cardiovascular conocida.

Introduction: Coronary artery calcification is a marker of atherosclerosis. Fluoroscopy is a simple and accessible method todetect coronary artery calcification.Objective: The aim of this study was to evaluate the value of fluoroscopic detection of coronary artery calcification as anindependent predictor of all-cause mortality and cardiovascular mortality in the long-term.Methods: A prospective cohort of persons ≥45 years without documented cardiovascular disease underwent fluoroscopicexamination to identify the presence of coronary artery calcification.A Cox regression model was used to evaluate the independent effect of calcification as a predictor of mortality in the long-term.Results: A total of 857 persons were included. Follow-up was completed in 98.7% of cases with an average of 14.4 ± 4.3 years(range: 34 days to 20.8 years). Mean age was 61.3 ± 9.7 years, 88.9% had hypertension, 19.6% had high cholesterol levels,1.8% were diabetics and 52.7% were men. Coronary artery calcification was detected in 264 patients (32%). The presence ofcoronary artery calcification was associated with age, male sex and high cholesterol levels.All-cause long-term mortality was 28.3% and cardiovascular mortality was 14.9%.The presence of coronary artery calcification was an independent predictor of all-cause mortality (HR 1.6, 95% CI 1.2-2.0;p = 0.002) and of cardiovascular mortality (HR 2.5, 95% CI 1.6-3.9; p = 0.002). All-cause mortality without calcification was1.35 per 100 patient-years and 3.39 per 100 patient-years with calcification [p (log rank test) &lt; 0.0001].Conclusion: Fluoroscopic detection of coronary artery calcification may predict all-cause mortality and cardiovascular mortalityin the long-term in a population without documented cardiovascular disease.

Metadatos destacados

Colecciones
Argentine Journal of Cardiology

Editor

Sociedad Argentina de Cardiología

Fuente

Revista Argentina de Cardiología; Vol 82, No 4 (2014); 322-325, Argentine Journal of Cardiology; Vol 82, No 4 (2014); 322-325

Citación

Caccavo, Alberto; CLINICA CORONEL SUÁREZ et al., “La calcificación coronaria detectada por fluoroscopia es capaz de predecir la mortalidad a largo plazo,” Archivo PPCT, consulta 2 de abril de 2026, http://archivoppct.caicyt.gov.ar/items/show/8397.

Dublin Core

Materia

Autor

Caccavo, Alberto; CLINICA CORONEL SUÁREZ
Brodsky, Rubén L.
Rolandi, Florencia
Caccavo, Francisco

Fuente

Revista Argentina de Cardiología; Vol 82, No 4 (2014); 322-325
Argentine Journal of Cardiology; Vol 82, No 4 (2014); 322-325

Editor

Sociedad Argentina de Cardiología

Fecha

2014-08-15

Derechos

Los que firman al pié, certificamos que tenemos total responsabilidad por la conducción de este estudio y por el diseño y la interpretación de los datos. Nosotros escribimos el manuscrito y somos responsables por la decisión acerca del mismo. Cada uno de nosotros cumple la definición de autor como se afirma en el Comité Internacional de Editores de Revistas Médicas (International Committee of Medical Journal Editors, ver www.icmje.org). Nosotros hemos visto y aprobado el manuscrito final. Ni el artículo, ni ninguna parte esencial del mismo, incluido las tablas y las figuras, será publicado o admitido para arbitrar a otra parte antes de aparecer en la Revista.También notificamos haber leído la sección “conflicto de intereses”, y revelaríamos cualquiera que existiera. Dejamos constancia que si nuestro artículo se publicara en la RAC, cederíamos los derechos (copyright) a la Revista.Los documentos publicados en esta revista están bajo la licencia Creative Commons Atribución-NoComercial-Compartir-Igual 2.5 Argentina.
Those signing below certify that we have full responsibility for the conduction of this study and for the design and interpretation of the information. We wrote the manuscript and are responsible for its decision. Each of us fulfills the definition of authorship as stated by the International Committee of Medical Journal Editors ( www.icmje.org). We have signed and approved the final manuscript. Neither the manuscript, nor any essential part thereof, including tables and figures, will be published or accepted for refereeing elsewhere before being published in the Journal. We have also read the "Conflict of Interest" section and would disclose any existing. We state that if our manuscript is published in the RAC, we shall transfer the copyright to the Journal.

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eng
spa

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info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion