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65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f trailer <]>> startxref 116 %%EOF Daño coronario secundario a enfermedad de Kawasaki - Archivo PPCT

Daño coronario secundario a enfermedad de Kawasaki;
Coronary Lesions in Kawasaki Disease

Creators:Schroh, Ana M., Melonari, Pablo A., Laghezza, Lidia B., Domínguez, Pablo J., Pierini, Florencia, Retamales, Eliana P., Rodríguez, María F., González, Gabriela E.
2015-03-03

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OBJETIVOS: Determinar la probabilidad de sufrir daño coronario en pacientes con enfermedad de Kawasaki (EK); reconocer los factores de riesgo para desarrollar lesión coronaria y la evolución a largo plazo de estos pacientes. MATERIAL Y MÉTODOS: Se diagnosticó EK a 245 niños (octubre 1988 -diciembre 2013) con edad media de 3.48 años. Las variables analizadas fueron: edad, sexo, criterios clínicos y de laboratorio de EK, hallazgos ecocardiográficos y evolución a largo plazo. Se calculó el Odds ratio para evaluar las diferentes variables analizadas como probables factores de riesgo de enfermedad coronaria. RESULTADOS: 39 pacientes presentaron daño coronario: 25 varones y 14 mujeres; edad media: 2.05 años. Se identificaron como factores de riesgo la edad &lt; 3 años; fiebre prolongada ≥ 6 días, eritrosedimentación &gt; 50 mm; proteína C reactiva &gt;100 mg/l y hematocrito &lt; 30%. 13 pacientes mostraron dilatación transitoria de las arterias coronarias; 12 pacientes aneurismas solitarios de pequeño o mediano tamaño; 7 pacientes aneurismas coronarios múltiples; 6 pacientes aneurismas coronarios gigantes y uno infarto agudo de miocardio por severa lesión obstructiva. La mortalidad hospitalaria fue del 4‰   CONCLUSIONES: La probabilidad de presentar daño coronario en pacientes con EK fue del 15.91%. Los factores de riesgo para lesión coronaria detectados fueron: edad menor a 3 años; 6 o más días de fiebre, eritrosedimentación &gt; 50mm; proteína C reactiva &gt;100 mg/l y hematocrito &lt; 30%. En los pacientes con daño coronario residual persistente tratados en forma convencional no hubo eventos adversos durante el seguimiento a mediano y largo plazo.

Background: Kawasaki disease, a vasculitis of unknown origin, is currently the main cause of acquired heart disease duringchildhood and its main sequelae are associated with coronary arteries. Therefore, early identification of possible coronarylesions enables adequate treatment to decrease their occurrence.Objectives: The aims of this study were to determine the probability of coronary injury in patients with Kawasaki disease, toidentify the risk factors for developing coronary lesions and the long-term outcome of these patients.Methods: A total of 245 children with mean age of 3.48 years were diagnosed with Kawasaki disease between October 1988and December 2013. Age, sex, clinical and laboratory criteria of Kawasaki disease, echocardiographic findings and long-termoutcome were analyzed and the odds ratio was used to assess their participation as probable risk factors for coronary lesions.Results: Thirty-nine patients presented coronary lesions: 25 male and 14 female patients with mean age of 2.05 years.Risk factors were: age &lt; 3 years; prolonged fever ≥ 6 days, erythrocyte sedimentation rate &gt; 50 mm; C-reactive protein &gt; 100mg/L and hematocrit &lt; 30%. Thirteen patients showed transient coronary artery dilation, 12 solitary small or medium sizeaneurysms, 7 multiple coronary aneurysms, 6 giant coronary aneurysms and one myocardial infarction by severe obstructivelesion. In-hospital mortality was 4‰.Conclusions: Risk of coronary artery lesions in patients with Kawasaki disease was 15.91%. Risk factors were age under 3years, fever lasting more than 6 days, erythrocyte sedimentation rate &gt; 50 mm; C-reactive protein &gt; 100 mg/L and hematocrit&lt; 30%. In patients with persistent residual coronary lesions treated conventionally there were no adverse events in themid- and long-term follow-up.

Metadatos destacados

Colecciones
Argentine Journal of Cardiology

Editor

Sociedad Argentina de Cardiología

Fuente

Revista Argentina de Cardiología; Vol 83, No 1 (2015); 8-13, Argentine Journal of Cardiology; Vol 83, No 1 (2015); 8-13

Citación

Schroh, Ana M. et al., “Daño coronario secundario a enfermedad de Kawasaki,” Archivo PPCT, consulta 2 de abril de 2026, http://archivoppct.caicyt.gov.ar/items/show/8411.

Dublin Core

Materia

Autor

Schroh, Ana M.
Melonari, Pablo A.
Laghezza, Lidia B.
Domínguez, Pablo J.
Pierini, Florencia
Retamales, Eliana P.
Rodríguez, María F.
González, Gabriela E.

Fuente

Revista Argentina de Cardiología; Vol 83, No 1 (2015); 8-13
Argentine Journal of Cardiology; Vol 83, No 1 (2015); 8-13

Editor

Sociedad Argentina de Cardiología

Fecha

2015-03-03

Derechos

Los que firman al pié, certificamos que tenemos total responsabilidad por la conducción de este estudio y por el diseño y la interpretación de los datos. Nosotros escribimos el manuscrito y somos responsables por la decisión acerca del mismo. Cada uno de nosotros cumple la definición de autor como se afirma en el Comité Internacional de Editores de Revistas Médicas (International Committee of Medical Journal Editors, ver www.icmje.org). Nosotros hemos visto y aprobado el manuscrito final. Ni el artículo, ni ninguna parte esencial del mismo, incluido las tablas y las figuras, será publicado o admitido para arbitrar a otra parte antes de aparecer en la Revista.También notificamos haber leído la sección “conflicto de intereses”, y revelaríamos cualquiera que existiera. Dejamos constancia que si nuestro artículo se publicara en la RAC, cederíamos los derechos (copyright) a la Revista.Los documentos publicados en esta revista están bajo la licencia Creative Commons Atribución-NoComercial-Compartir-Igual 2.5 Argentina.
Those signing below certify that we have full responsibility for the conduction of this study and for the design and interpretation of the information. We wrote the manuscript and are responsible for its decision. Each of us fulfills the definition of authorship as stated by the International Committee of Medical Journal Editors ( www.icmje.org). We have signed and approved the final manuscript. Neither the manuscript, nor any essential part thereof, including tables and figures, will be published or accepted for refereeing elsewhere before being published in the Journal. We have also read the "Conflict of Interest" section and would disclose any existing. We state that if our manuscript is published in the RAC, we shall transfer the copyright to the Journal.

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eng
spa

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info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion