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esclerodermia sin antecedentes cardiovasculares - Archivo PPCT

Hallazgos ecocardiograficos en pacientes con esclerodermia sin antecedentes cardiovasculares;
Echocardiographic Findings in Scleroderma without History of Cardiovascular Disease

Creators:Beck, Martín; Revista de la Sociedad Argentina de Cardiología, Lescano, Adrián, Lescano, Adrián, Gómez, Gastón, Nittchel, Alejandro, Salvatierra, Alejandro, De Valais, Fernando
2014-04-14

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Descripción

INTRODUCCIÓN La esclerodermia es una  enfermedad del tejido conectivo caracterizado por extensa fibrosis cutánea y de diversos órganos. La Insuficiencia cardíaca y la hipertensión pulmonar son síndromes cardiovasculares asociados con esta entidad que determinan pronóstico. La ecocardiografía doppler cumple un rol fundamental en la evaluación anatómica y funcional de las estructuras cardíacas en la esclerodermia y permite el diagnóstico de alteraciones incipientes, en la relajación o mecánica segmentaria ventricular, entre otras, además de la evaluación de la presencia y grado de hipertensión pulmonar. Objetivo Describir los hallazgos ecocardiográficos relevantes en pacientes con diagnóstico de esclerodermia sin antecedentes cardiovasculares. Material y Métodos Estudio de corte transversal  y descriptivo de 46 pacientes (ptes) con diagnóstico establecido de esclerodermia, que asistieron al laboratorio de ecocardiografía por control de rutinario. Se realizó el análisis del ventrículo izquierdo (VI): función sistólica (FSVI) a través de fracción de eyección (FEY). Se definió deterioro de FSVI con Fey &lt; 50% diámetro sistólico (DS) y diastólico (DD), espesores parietales, asinergias regionales (AR), función diastólica (ondas E y A, relación del flujo transmitral) que se definió como normal, tipo I (alteración de relajación), tipo II (pseudonormal), tipo III (restrictivo); doppler tisular septal y  lateral (DTI) con onda S,E y A, relación E/E´. Aurícula izquierda (AI): área en cm2 y dilatación se considero con valores &gt; 20 cm2. Ventrículo derecho: Función sistólica (FSVD) cualitativa, TAPSE (excursión del anillo tricúspideo), diámetro diastólico (DDVD) a nivel basal, doppler tisular lateral (DTVD) con determinación de onda S, E y A, función diastólica (FDVD) por ondas E, A y relación del flujo tricúspideo. Presión pulmonar sistólica (PPS) a través de la sumatoria del gradiente del reflujo tricúspideo y la presión de aurícula derecha (diámetro de vena cava inferior y colapso inspiratorio). Se cuantificó la presencia de valvulopatías significativas. Resultados Se incluyeron 46 ptes con una edad media de 50 años, sexo femenino 84%, hipertensión arterial 26%, tabaquismo 24%. Entre los hallazgos ecocardiográficos se observan: FSVI conservada en el 98%, FEy promedio de 62%, septum interventricular 9,7mm, DDVI 43 mm, AR 2% (1 pte), la FDVI fue normal 48%, tipo I 44%, tipo II 2% y tipo III 4%. El DTVI presentó una onda S promedio de 11 cm/seg y valores &lt; 11 en el 45%, con una relación E/E’ de 5 (0% &gt; 10). El área de AI 18 cm2 y dilatación en el 24%. VD: FSVD normal 96% (44), DDVD 32 mm, TAPSE  24 mm, trastorno de relajación del VD 26%, DTVD.S 14 cm/seg;  PPS promedio de 40 mm Hg (25-110 mm Hg), con diagnóstico de HP en 48% (22 ptes). El incremento de los valores de PPS ≥ 50 mm Hg (moderado-severo) alcanzó al 15% (7 ptes). Derrame pericárdico en 4 ptes. No se observaron valvulopatías significativas. Conclusiones Entre los hallazgos ecocardiográficos de los pacientes con esclerodermia sin antecedentes cardiovasculares se observó una elevada prevalencia de disfunción diastólica leve del VI y del VD, dilatación de AI, disminución de la onda S del DT VI (menor contracción longitudinal regional) y elevado porcentaje de hipertensión pulmonar (48%).

Metadatos destacados

Colecciones
Argentine Journal of Cardiology

Editor

Sociedad Argentina de Cardiología

Fuente

Revista Argentina de Cardiología; Vol 82, No 2 (2014); 105-109, Argentine Journal of Cardiology; Vol 82, No 2 (2014); 105-109

Citación

Beck, Martín; Revista de la Sociedad Argentina de Cardiología et al., “Hallazgos ecocardiograficos en pacientes con esclerodermia sin antecedentes cardiovasculares,” Archivo PPCT, consulta 2 de abril de 2026, http://archivoppct.caicyt.gov.ar/items/show/8530.

Dublin Core

Autor

Beck, Martín; Revista de la Sociedad Argentina de Cardiología
Lescano, Adrián
Lescano, Adrián
Gómez, Gastón
Nittchel, Alejandro
Salvatierra, Alejandro
De Valais, Fernando

Fuente

Revista Argentina de Cardiología; Vol 82, No 2 (2014); 105-109
Argentine Journal of Cardiology; Vol 82, No 2 (2014); 105-109

Editor

Sociedad Argentina de Cardiología

Fecha

2014-04-14

Derechos

Los que firman al pié, certificamos que tenemos total responsabilidad por la conducción de este estudio y por el diseño y la interpretación de los datos. Nosotros escribimos el manuscrito y somos responsables por la decisión acerca del mismo. Cada uno de nosotros cumple la definición de autor como se afirma en el Comité Internacional de Editores de Revistas Médicas (International Committee of Medical Journal Editors, ver www.icmje.org). Nosotros hemos visto y aprobado el manuscrito final. Ni el artículo, ni ninguna parte esencial del mismo, incluido las tablas y las figuras, será publicado o admitido para arbitrar a otra parte antes de aparecer en la Revista.También notificamos haber leído la sección “conflicto de intereses”, y revelaríamos cualquiera que existiera. Dejamos constancia que si nuestro artículo se publicara en la RAC, cederíamos los derechos (copyright) a la Revista.Los documentos publicados en esta revista están bajo la licencia Creative Commons Atribución-NoComercial-Compartir-Igual 2.5 Argentina.
Those signing below certify that we have full responsibility for the conduction of this study and for the design and interpretation of the information. We wrote the manuscript and are responsible for its decision. Each of us fulfills the definition of authorship as stated by the International Committee of Medical Journal Editors ( www.icmje.org). We have signed and approved the final manuscript. Neither the manuscript, nor any essential part thereof, including tables and figures, will be published or accepted for refereeing elsewhere before being published in the Journal. We have also read the "Conflict of Interest" section and would disclose any existing. We state that if our manuscript is published in the RAC, we shall transfer the copyright to the Journal.

Formato

Idioma

spa
eng

Tipo

info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion