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Endocarditis infecciosa en la miocardiopatía hipertrófica;
Infective Endocarditis in Hypertrophic Cardiomyopathy

Creators:Casabé, J. Horacio; Hospital Universitario Fundación Favaloro.
Av. Belgrano 1746, (C1093AAS) Buenos Aires, Argentina., Fernández, Adrián, Renedo, María F., Guevara, Eduardo, Favaloro, Liliana E., Favaloro, Roberto R.
2015-08-25

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Descripción

Introducción: La endocarditis infecciosa (EI) es una complicación reconocida de la miocardiopatía hipertrófica (MCH); elimplante de dispositivos intracavitarios (DI) para el tratamiento de la MCH agrega un factor que incrementa el riesgo de EI.Objetivo: Analizar la incidencia, las manifestaciones clínicas y el pronóstico de la EI en pacientes con MCH.Material y métodos: Estudio retrospectivo, descriptivo y observacional. Se evaluaron la ocurrencia de EI y las característicasclínicas de una población con diagnóstico de MCH desde junio de 1992 hasta enero de 2014, con una mediana de seguimientode 7,5 años.Resultados: Se evaluaron 646 pacientes con MCH. El 38,5% (n = 230) presentó obstrucción al tracto de salida del ventrículoizquierdo (OTSVI) y el 22% (n = 129) tenía un DI. La incidencia de EI fue del 1,9%. Se evidenciaron 12 episodios, 7 valvulares[7/230 (3,04%)] y 5 en DI, 3 en marcapasos y 2 en cardiodesfibrilador [5/129 (6,45%)]. Los pacientes con EI valvular presentabanun gradiente promedio de 48 ± 37 mm Hg en reposo y de 126 ± 44 mm Hg durante Valsalva. Todos respondieron altratamiento médico. En 5 pacientes con EI en el DI se efectuó la extracción percutánea. Un paciente (8%) del grupo valvularrequirió reemplazo; ningún paciente falleció.Conclusiones: La EI en la MCH tiene una incidencia baja. Existen dos poblaciones definidas: EI valvular izquierda, confinadaen pacientes con OTSVI y EI por DI. Los pacientes con MCH sin OTSVI ni DI no presentaron EI.

Background: Infective endocarditis (IE) is a well-known complication of hypertrophic cardiomyopathy (HCM). Intracardiacdevice (ID) implantation for the treatment of HCM is an additional factor that increases the risk of IE.Objective: The aim of this study was to assess the clinical manifestations and prognosis of IE in patients with HCM.Methods: A retrospective, descriptive and observational study assessed the occurrence of IE and the clinical characteristicsof a population with HCM from June 1992 to January 2014, with median follow-up of 7.5 years.Results: The study evaluated 646 patients with HCM. Left ventricular outflow tract obstruction (LVOTO) was present in38.5% (n=230) of patients and 22% (n=129) had an ID. The incidence of IE was 1.9%. Twelve episodes were confirmed, 7valvular [7/230 (3.04%)] and 5 in ID, 3 in pacemakers and 2 in implantable cardioverter defibrillators [5/129 (6.45%)]. Patientswith valvular IE had resting mean gradient of 48±37 mmHg and during Valsalva maneuver of 126±44 mmHg, respondingto medical treatment in all cases. Infective endocarditis in ID was resolved with percutaneous removal in 5 patients. Onepatient of the valvular group (8%) required valve replacement. No deaths were reported.Conclusions: The incidence of IE in HCM is low. There are two defined populations: left valvular IE confined to patients withLVOTO and IE for ID. Patients with HCM without LVOTO or ID did not present IE.

Metadatos destacados

Colecciones
Argentine Journal of Cardiology

Editor

Sociedad Argentina de Cardiología

Fuente

Revista Argentina de Cardiología; Vol 83, No 4 (2015); 335-338, Argentine Journal of Cardiology; Vol 83, No 4 (2015); 335-338

Citación

Casabé, J. Horacio; Hospital Universitario Fundación Favaloro. Av. Belgrano 1746, (C1093AAS) Buenos Aires, Argentina. et al., “Endocarditis infecciosa en la miocardiopatía hipertrófica,” Archivo PPCT, consulta 2 de abril de 2026, http://archivoppct.caicyt.gov.ar/items/show/8856.

Dublin Core

Autor

Casabé, J. Horacio; Hospital Universitario Fundación Favaloro.
Av. Belgrano 1746, (C1093AAS) Buenos Aires, Argentina.
Fernández, Adrián
Renedo, María F.
Guevara, Eduardo
Favaloro, Liliana E.
Favaloro, Roberto R.

Fuente

Revista Argentina de Cardiología; Vol 83, No 4 (2015); 335-338
Argentine Journal of Cardiology; Vol 83, No 4 (2015); 335-338

Editor

Sociedad Argentina de Cardiología

Fecha

2015-08-25

Derechos

Los que firman al pié, certificamos que tenemos total responsabilidad por la conducción de este estudio y por el diseño y la interpretación de los datos. Nosotros escribimos el manuscrito y somos responsables por la decisión acerca del mismo. Cada uno de nosotros cumple la definición de autor como se afirma en el Comité Internacional de Editores de Revistas Médicas (International Committee of Medical Journal Editors, ver www.icmje.org). Nosotros hemos visto y aprobado el manuscrito final. Ni el artículo, ni ninguna parte esencial del mismo, incluido las tablas y las figuras, será publicado o admitido para arbitrar a otra parte antes de aparecer en la Revista.También notificamos haber leído la sección “conflicto de intereses”, y revelaríamos cualquiera que existiera. Dejamos constancia que si nuestro artículo se publicara en la RAC, cederíamos los derechos (copyright) a la Revista.Los documentos publicados en esta revista están bajo la licencia Creative Commons Atribución-NoComercial-Compartir-Igual 2.5 Argentina.
Those signing below certify that we have full responsibility for the conduction of this study and for the design and interpretation of the information. We wrote the manuscript and are responsible for its decision. Each of us fulfills the definition of authorship as stated by the International Committee of Medical Journal Editors ( www.icmje.org). We have signed and approved the final manuscript. Neither the manuscript, nor any essential part thereof, including tables and figures, will be published or accepted for refereeing elsewhere before being published in the Journal. We have also read the "Conflict of Interest" section and would disclose any existing. We state that if our manuscript is published in the RAC, we shall transfer the copyright to the Journal.

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eng
spa

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info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion