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REGISTRO EPI-CARDIO. - Archivo PPCT

ESTATINAS AL ALTA EN LA CORONARIOPATÍA AGUDA EN LOS ÚLTIMOS 10 AÑOS. REGISTRO EPI-CARDIO.;
Statins at Discharge in Acute Coronary Syndromes over the past 10 Years. The Epi-Cardio Registry

Creators:Travetto, Carolina Mercedes; Hospital de Alta Complejidad en Red El Cruce "Dr. Néstor C. Kirchner" SAMIC., Bacigalupe, Juan José; Hospital de Alta Complejidad en Red El Cruce "Dr. Néstor C. Kirchner" SAMIC., Martínez, María José; Hospital de Alta Complejidad en Red El Cruce "Dr. Néstor C. Kirchner" SAMIC., de Abreu, Maximiliano; Hospital de Alta Complejidad en Red El Cruce "Dr. Néstor C. Kirchner" SAMIC.
Grupo de Estudio, Docencia e Investigación Clínica (GEDIC), Mariani, Javier; Hospital de Alta Complejidad en Red El Cruce "Dr. Néstor C. Kirchner" SAMIC.
Grupo de Estudio, Docencia e Investigación Clínica (GEDIC)., Sosa Liprandi, Álvaro; Sanatorio Güemes.
Instituto Cardiovascular Lezica.
Grupo de Estudio, Docencia e Investigación Clínica (GEDIC)., Charask, Adrián; Clínica Bazterrica-Santa Isabel.
Grupo de Estudio, Docencia e Investigación Clínica (GEDIC)., Gagliardi, Juan; Hospital General de Agudos “Dr. Cosme Argerich”.
Grupo de Estudio, Docencia e Investigación Clínica (GEDIC)., Doval, Hernán; Grupo de Estudio, Docencia e Investigación Clínica (GEDIC)., Tajer, Carlos; Hospital de Alta Complejidad en Red El Cruce "Dr. Néstor C. Kirchner" SAMIC.
Grupo de Estudio, Docencia e Investigación Clínica (GEDIC).
2017-01-05

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Descripción

OBJETIVO: Evaluar el empleo de estatinas al alta en pacientes con síndrome coronario agudo incluidos en el registro Epi-Cardio y su variación en los últimos 10 años. MATERIAL Y  METODO: Se incluyeron los pacientes con síndrome coronario agudo ingresados entre 2005 y 2014, excluyendo fallecidos o sin datos del tratamiento al alta. Se analizó la frecuencia de indicación de estatinas, fármacos y dosis utilizadas a lo largo de los 10 años, así como la indicación de terapia de alta intensidad (rosuvastatina 20-40mg, atorvastatina 40-80mg). Se comparó el uso de acuerdo al ámbito de atención de la salud. RESULTADOS: Se analizaron 22905 registros. Los fármacos más empleados fueron atorvastatina 68%, simvastatina 22,7% y rosuvastatina 9,1%. Las tendencias temporales fueron significativas hacia el incremento de la indicación de estatinas (83% en 2005-2007 a 92,5% en 2014), aumento de las dosis, reducción de la indicación de simvastatina en favor de los otros agentes, e incremento de la terapia de alta intensidad de 7,7% en 2005-2007 al 52,6% en 2014. El empleo de terapia de alta intensidad fue menor en el ámbito público. CONCLUSION: La frecuencia de indicación de estatinas se acerca a niveles óptimos, y el empleo de dosis elevadas se incrementó durante el período de estudio alcanzando a más de la mitad de los pacientes. Las diferencias en el sector público sugieren un menor acceso al tratamiento. Son necesarios estudios adicionales que identifiquen las barreras para implementar los regímenes de elevada intensidad.

Background: Statins have been incorporated for secondary prevention of cardiovascular disease for over two decades, with a remarkable impact in reducing morbidity and mortality. Currently, the evidence available recommends the use of high-intensity statin therapy in all the patients presenting an acute coronary syndrome. Objective: The aim of this study was to evaluate the use of statins at discharge in acute coronary syndrome patients included in the Epi-Cardio registry and its variation over the past 10 years. Methods: Patients hospitalized between 2005 and 2014 with diagnosis of acute coronary syndrome were included; those deceased or without data of the treatment at discharge were excluded. The frequency of indication of statins, agents, doses used over the 10-year period and the indication of high-intensity therapy (rosuvastatin 20-40 mg, atorvastatin 40-80 mg) were analyzed. The use according to the field of care was compared. Results: 22,905 records were analyzed. The most common agents used were atorvastatin 68%, simvastatin 22.7% and rosuvastatin 9.1%. The temporal trend revealed higher frequency of statin prescription (from 83% in 2005-2007 to 92.5% in 2014), higher doses, lower indication of simvastatin and higher of other agents, and greater use of high-intensity statin therapy from 7.7% in 2005-2007 to 52.6% in 2014. The use of high-intensity therapy was lower in the public health care system.Conclusions: The frequency of statin indication reaches optimal levels and the use of high-intensity therapy increased during the period evaluated, including over half of the patients. The differences in the public health care system suggest a lower access to treatment. Additional studies are necessary to identify the barriers for implementing high-intensity statin therapy.

Metadatos destacados

Colecciones
Argentine Journal of Cardiology

Editor

Sociedad Argentina de Cardiología

Fuente

Revista Argentina de Cardiología; Vol 84, No 5 (2016); 459-467, Argentine Journal of Cardiology; Vol 84, No 5 (2016); 459-467

Citación

Travetto, Carolina Mercedes; Hospital de Alta Complejidad en Red El Cruce "Dr. Néstor C. Kirchner" SAMIC. et al., “ESTATINAS AL ALTA EN LA CORONARIOPATÍA AGUDA EN LOS ÚLTIMOS 10 AÑOS. REGISTRO EPI-CARDIO.,” Archivo PPCT, consulta 1 de abril de 2026, http://archivoppct.caicyt.gov.ar/items/show/9145.

Dublin Core

Materia

Autor

Travetto, Carolina Mercedes; Hospital de Alta Complejidad en Red El Cruce "Dr. Néstor C. Kirchner" SAMIC.
Bacigalupe, Juan José; Hospital de Alta Complejidad en Red El Cruce "Dr. Néstor C. Kirchner" SAMIC.
Martínez, María José; Hospital de Alta Complejidad en Red El Cruce "Dr. Néstor C. Kirchner" SAMIC.
de Abreu, Maximiliano; Hospital de Alta Complejidad en Red El Cruce "Dr. Néstor C. Kirchner" SAMIC.
Grupo de Estudio, Docencia e Investigación Clínica (GEDIC)
Mariani, Javier; Hospital de Alta Complejidad en Red El Cruce "Dr. Néstor C. Kirchner" SAMIC.
Grupo de Estudio, Docencia e Investigación Clínica (GEDIC).
Sosa Liprandi, Álvaro; Sanatorio Güemes.
Instituto Cardiovascular Lezica.
Grupo de Estudio, Docencia e Investigación Clínica (GEDIC).
Charask, Adrián; Clínica Bazterrica-Santa Isabel.
Grupo de Estudio, Docencia e Investigación Clínica (GEDIC).
Gagliardi, Juan; Hospital General de Agudos “Dr. Cosme Argerich”.
Grupo de Estudio, Docencia e Investigación Clínica (GEDIC).
Doval, Hernán; Grupo de Estudio, Docencia e Investigación Clínica (GEDIC).
Tajer, Carlos; Hospital de Alta Complejidad en Red El Cruce "Dr. Néstor C. Kirchner" SAMIC.
Grupo de Estudio, Docencia e Investigación Clínica (GEDIC).

Fuente

Revista Argentina de Cardiología; Vol 84, No 5 (2016); 459-467
Argentine Journal of Cardiology; Vol 84, No 5 (2016); 459-467

Editor

Sociedad Argentina de Cardiología

Fecha

2017-01-05

Derechos

Los que firman al pié, certificamos que tenemos total responsabilidad por la conducción de este estudio y por el diseño y la interpretación de los datos. Nosotros escribimos el manuscrito y somos responsables por la decisión acerca del mismo. Cada uno de nosotros cumple la definición de autor como se afirma en el Comité Internacional de Editores de Revistas Médicas (International Committee of Medical Journal Editors, ver www.icmje.org). Nosotros hemos visto y aprobado el manuscrito final. Ni el artículo, ni ninguna parte esencial del mismo, incluido las tablas y las figuras, será publicado o admitido para arbitrar a otra parte antes de aparecer en la Revista.También notificamos haber leído la sección “conflicto de intereses”, y revelaríamos cualquiera que existiera. Dejamos constancia que si nuestro artículo se publicara en la RAC, cederíamos los derechos (copyright) a la Revista.Los documentos publicados en esta revista están bajo la licencia Creative Commons Atribución-NoComercial-Compartir-Igual 2.5 Argentina.
Those signing below certify that we have full responsibility for the conduction of this study and for the design and interpretation of the information. We wrote the manuscript and are responsible for its decision. Each of us fulfills the definition of authorship as stated by the International Committee of Medical Journal Editors ( www.icmje.org). We have signed and approved the final manuscript. Neither the manuscript, nor any essential part thereof, including tables and figures, will be published or accepted for refereeing elsewhere before being published in the Journal. We have also read the "Conflict of Interest" section and would disclose any existing. We state that if our manuscript is published in the RAC, we shall transfer the copyright to the Journal.

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eng
spa

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info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion