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Registro CONAREC XX - Archivo PPCT

Tromboembolismo pulmonar agudo en la Argentina. Registro CONAREC XX;
Acute Pulmonary Embolism in Argentina. XX CONAREC Registry

Creators:Cigalini, Ignacio, Igolnikof, Dario Ben, Scatularo, Cristhian E., Jauregui, Juan C., Bernal, Maico I., García Zamora, Sebastián, Bonorino, José M., Thierer, Jorge, Zaidel, Ezequiel J.
2019-04-11

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Descripción

Introducción: El tromboembolismo de pulmón agudo (TEP) representa la tercera causa de mortalidad cardiovascular. Sinembargo, existen pocos datos de esta patología en nuestro país. Nuestro objetivo fue describir las características basales,evolución y tratamiento implementado en pacientes con tromboembolismo de pulmón agudo en Argentina.Material y métodos: Se trata de un registro multicéntrico prospectivo que incorporó pacientes con diagnóstico de tromboembolismode pulmón agudo internados en centros con residencia de cardiología desde octubre de 2016 a noviembre de 2017. Serealizó un análisis convencional para estadística descriptiva y comparativa. Se consideró significativo un valor de p &lt; 0,05.Se realizó una auditoría cruzada al 20% de los centros participantes.Resultados: Se incluyeron 684 pacientes consecutivos de 75 centros, con un promedio de edad de 63,8 años; 388 (57%) erande sexo femenino. El TEP fue el motivo de internación en 484 (71%) de los casos. Los factores predisponentes más frecuentesfueron obesidad, hospitalización reciente, reposo transitorio y cáncer activo. Se indicó anticoagulación durante la internaciónen 661 (97%) pacientes y terapia de reperfusión en 91 (13%). Sin embargo, solo 50 de los 102 pacientes que se presentaroncon inestabilidad hemodinámica recibieron alguna terapia de reperfusión (49%). La mortalidad hospitalaria fue del 12%,principalmente relacionada con el tromboembolismo de pulmón agudo (51%).Conclusiones: El tromboembolismo de pulmón agudo en nuestro medio constituye una patología con elevada mortalidad enla internación atribuible principalmente al evento embólico. Se observó una baja utilización de terapias de reperfusión enpacientes con inestabilidad hemodinámica.

Background: Acute pulmonary embolism (PE) represents the third cause of cardiovascular mortality. However, there is lackof information about this entity in our country. Our aim was to describe baseline characteristics, clinical evolution and treatmentof patients with acute PE in Argentina.Methods: This was a prospective multicenter registry including patients with acute PE hospitalized in centers with cardiologyresidency from October 2016 to November 2017. Conventional analysis was performed for descriptive and comparativestatistics. A value of p&lt;0.05 was considered significant. Cross audit was performed to 20% of participating centers.Results: We included 684 consecutive patients from 75 centers with an average age of 63.8 years and 388 (57%) women. Hospitaladmission was due to PE in 484 (71%) cases. The most frequent predisposing factors were obesity, recent hospitalization,transient rest and active cancer. Anticoagulation was indicated in 661 patients (97%) and reperfusion therapy was performedin 91 (13%). However, only 50 of the 102 patients who presented with hemodynamic instability received reperfusion therapy(49%). Global in-hospital mortality was 12%, mainly associated with acute PE (51%).Conclusions: Acute pulmonary embolism presents with high in-hospital mortality in our setting, mainly related to the embolicevent. We observed a low use of reperfusion therapies in patients with hemodynamic instability.

Metadatos destacados

Colecciones
Argentine Journal of Cardiology

Editor

Sociedad Argentina de Cardiología

Fuente

Revista Argentina de Cardiología; Vol 87, No 2 (2019); 131-136, Argentine Journal of Cardiology; Vol 87, No 2 (2019); 131-136

Citación

Cigalini, Ignacio et al., “Tromboembolismo pulmonar agudo en la Argentina. Registro CONAREC XX,” Archivo PPCT, consulta 4 de abril de 2026, http://archivoppct.caicyt.gov.ar/items/show/9554.

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Materia

Autor

Cigalini, Ignacio
Igolnikof, Dario Ben
Scatularo, Cristhian E.
Jauregui, Juan C.
Bernal, Maico I.
García Zamora, Sebastián
Bonorino, José M.
Thierer, Jorge
Zaidel, Ezequiel J.

Fuente

Revista Argentina de Cardiología; Vol 87, No 2 (2019); 131-136
Argentine Journal of Cardiology; Vol 87, No 2 (2019); 131-136

Editor

Sociedad Argentina de Cardiología

Fecha

2019-04-11

Derechos

Los que firman al pié, certificamos que tenemos total responsabilidad por la conducción de este estudio y por el diseño y la interpretación de los datos. Nosotros escribimos el manuscrito y somos responsables por la decisión acerca del mismo. Cada uno de nosotros cumple la definición de autor como se afirma en el Comité Internacional de Editores de Revistas Médicas (International Committee of Medical Journal Editors, ver www.icmje.org). Nosotros hemos visto y aprobado el manuscrito final. Ni el artículo, ni ninguna parte esencial del mismo, incluido las tablas y las figuras, será publicado o admitido para arbitrar a otra parte antes de aparecer en la Revista.También notificamos haber leído la sección “conflicto de intereses”, y revelaríamos cualquiera que existiera. Dejamos constancia que si nuestro artículo se publicara en la RAC, cederíamos los derechos (copyright) a la Revista.Los documentos publicados en esta revista están bajo la licencia Creative Commons Atribución-NoComercial-Compartir-Igual 2.5 Argentina.
Those signing below certify that we have full responsibility for the conduction of this study and for the design and interpretation of the information. We wrote the manuscript and are responsible for its decision. Each of us fulfills the definition of authorship as stated by the International Committee of Medical Journal Editors ( www.icmje.org). We have signed and approved the final manuscript. Neither the manuscript, nor any essential part thereof, including tables and figures, will be published or accepted for refereeing elsewhere before being published in the Journal. We have also read the "Conflict of Interest" section and would disclose any existing. We state that if our manuscript is published in the RAC, we shall transfer the copyright to the Journal.

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eng
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info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion