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65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f trailer <]>> startxref 116 %%EOF ¿La prueba del frío podría predecir la aparición de eventos cardiovasculares en pacientes sin enfermedad coronaria demostrada? - Archivo PPCT

¿La prueba del frío podría predecir la aparición de eventos cardiovasculares en pacientes sin enfermedad coronaria demostrada?;
Is Cold Pressor Test Useful to Predict Cardiovascular Events in Patients with Not Documented Coronary Artery Disease?

Creators:Pautasso, Enrique; Doctor en Medicina Interna, Koretzky, Martin, Aiub, Jorge, Foye, Ricardo, Borrego, Carlos, De Cecco, Fabian, Marcon, Leopoldo, Boscaro, Marcelo, Panini, Julio, Lerman, Jorge
2011-12-20

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Descripción

RESUMENIntroducciónLa disfunción endotelial es la primera alteración conocida que interviene en el desarrollo de la cardiopatía isquémica. La falta de metodologías adecuadamente desarrolladas que permitan reconocer en la etapa preclínica de la enfermedad a los pacientes en riesgo de padecer un evento cardiovascular alertan sobre la necesidad de adoptar métodos adicionales de diagnóstico para su identificación precoz. La función endotelial en las arterias coronarias fue evaluada con perfusión miocárdica SPECT y la prueba del frío.ObjetivosDeterminar la prevalencia de la prueba del frío en 511 pacientes sin cardiopatía isquémica demostrada, como también de los factores de riesgo coronario asociados en aquellos con resultado positivo y analizar la incidencia de eventos cardiovasculares en un seguimiento de cincuenta meses.

SUMMARY To determine the prevalence of the cold pressor test in 511 patients with no proved ischemic heart disease, as well as, the associated coronary risk factors in those patients with a positive result and to analyze the incidence of cardiovascular events in a 50-month monitoring.Material and MethodsA tomographic study of myocardial perfusion SPECT imaging was performed in 511 patients in a department of nuclear medicine, whose result versus the exercise showed uniform radiotracer uptake. No patient had history of myocardial revascularization or previous myocardial infarction. The cold pressor test was performed within 5 days after the admission protocol. The test is positive when radioisotope hypo-uptake is observed at any segment that was not present in the cardiac stress test and it is negative when there are no changes in the uptake between both studies.The average monitoring was 24±13 months, which could be completed in 95% of the patients. Cardiac mortality, myocardial infarction, cerebrovascular accident and revascularization procedures were analyzed.ResultsThe mean age was 58.7 years with a prevalence of 52.6% in men. Prevalence of risk factors: diabetes 10.3%, dyslipidemia 69.3%, hypertension 63.4%, obesity 25.2%, and tobacco smoking 22.3%.The test was positive in 32.4% of the patients. 3.9% of the patients did not tolerate a cold stimulus and 5.3% had vasovagal response.During 50 months, the event-free survival was 95.6% and 86.6% in patients with negative and positive test, respectively (p &lt; 0.01).ConclusionsThe prevalence of the positive cold pressor test in patients with no proved ischemic heart disease was 32.4%. Men and high body mass index were associated with a positive test. The positive cold pressor test would identify patients who could suffer from cardiovascular events.REV ARGENT CARDIOL 2010;78:417-424.    Objective

Metadatos destacados

Colecciones
Argentine Journal of Cardiology

Editor

Sociedad Argentina de Cardiología

Fuente

Revista Argentina de Cardiología; Vol 78, No 5 (2010); 417-424, Argentine Journal of Cardiology; Vol 78, No 5 (2010); 417-424

Citación

Pautasso, Enrique; Doctor en Medicina Interna et al., “¿La prueba del frío podría predecir la aparición de eventos cardiovasculares en pacientes sin enfermedad coronaria demostrada?,” Archivo PPCT, consulta 2 de abril de 2026, http://archivoppct.caicyt.gov.ar/items/show/8031.

Dublin Core

Materia

Autor

Pautasso, Enrique; Doctor en Medicina Interna
Koretzky, Martin
Aiub, Jorge
Foye, Ricardo
Borrego, Carlos
De Cecco, Fabian
Marcon, Leopoldo
Boscaro, Marcelo
Panini, Julio
Lerman, Jorge

Fuente

Revista Argentina de Cardiología; Vol 78, No 5 (2010); 417-424
Argentine Journal of Cardiology; Vol 78, No 5 (2010); 417-424

Editor

Sociedad Argentina de Cardiología

Fecha

2011-12-20

Derechos

Los que firman al pié, certificamos que tenemos total responsabilidad por la conducción de este estudio y por el diseño y la interpretación de los datos. Nosotros escribimos el manuscrito y somos responsables por la decisión acerca del mismo. Cada uno de nosotros cumple la definición de autor como se afirma en el Comité Internacional de Editores de Revistas Médicas (International Committee of Medical Journal Editors, ver www.icmje.org). Nosotros hemos visto y aprobado el manuscrito final. Ni el artículo, ni ninguna parte esencial del mismo, incluido las tablas y las figuras, será publicado o admitido para arbitrar a otra parte antes de aparecer en la Revista.También notificamos haber leído la sección “conflicto de intereses”, y revelaríamos cualquiera que existiera. Dejamos constancia que si nuestro artículo se publicara en la RAC, cederíamos los derechos (copyright) a la Revista.Los documentos publicados en esta revista están bajo la licencia Creative Commons Atribución-NoComercial-Compartir-Igual 2.5 Argentina.
Those signing below certify that we have full responsibility for the conduction of this study and for the design and interpretation of the information. We wrote the manuscript and are responsible for its decision. Each of us fulfills the definition of authorship as stated by the International Committee of Medical Journal Editors ( www.icmje.org). We have signed and approved the final manuscript. Neither the manuscript, nor any essential part thereof, including tables and figures, will be published or accepted for refereeing elsewhere before being published in the Journal. We have also read the "Conflict of Interest" section and would disclose any existing. We state that if our manuscript is published in the RAC, we shall transfer the copyright to the Journal.

Formato

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spa
eng

Tipo

info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion