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Hipertensión de guardapolvo blanco: evolución a hipertensión sostenida luego de 10 años de seguimiento;
Progression of White Coat Hypertension to Sustained Hypertension After 10 Year Follow-up

Creators:Paez, Olga B., Puleio, Pablo A., Gorocito, Marta G., Visser, Miguel, Schiavone, Miguel, Majul, Claudio R.
2012-05-28

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Descripción

IntroducciónNo obstante la amplia información en la bibliografía sobre la caracterización de la hipertensión de guardapolvo blanco (HGB), su evolución alejada es hasta el presente tema de controversia. ObjetivoEvaluar la incidencia acumulada de hipertensión sostenida (HS) en hipertensos de guardapolvo blanco respecto de normotensos a los 10 años de su inclusión en el estudio.Material y métodosSe incorporaron en forma prospectiva 250 pacientes de ambos sexos, según los siguientes valores de presión de consultorio (PC) y de monitoreo ambulatorio de la presión arterial (MAPA) de 24 horas:HGB HS NormotensiónPC (mm Hg) ≥ 140 y/o 90 ≥ 140 y/o 90 ≤ 140 y/o 90MAPA (mm Hg) ≤ 135 y 85 ≥ 135 y 85 ≤ 135 y 85Se conformaron dos grupos: 129 hipertensos de guardapolvo blanco y 121 normotensos, los cuales fueron evaluados nuevamente a los 10 años de seguimiento. Se midieron la glucemia, el perfil lipídico y el índice de masa ventricular izquierda (IMVI). ResultadosLas variables edad, sexo, tabaquismo y glucemia de normotensos e hipertensos de guardapolvo blanco fueron similares en el examen basal. Los hipertensos de guardapolvo blanco, por el contrario, presentaron valores significativamente superiores en IMC, colesterol total, hipertrigliceridemia e IMVI. Cuarenta y ocho hipertensos de guardapolvo blanco y 21 normotensos originales evolucionaron a HS. La HGB se asoció en forma independiente con HS a los 10 años de seguimiento [OR: 2,5 (IC 95% 1,2-4,2)]. ConclusiónLa evolución a hipertensión sostenida fue mayor en los hipertensos de guardapolvo blanco que en los normotensos. 

Background The long-term outcome of white coat hypertension (WCH) is still controversial despite the broad information currently available. Objective To evaluate the cumulative incidence of sustained hypertension (SH) among patients with white coat hypertension compared to normotensive patients 10 years after being included in the study. Material and Methods A total of 250 patients of both genders were prospectively included with the following office blood pressure (OBP) and 24-hour ambulatory blood pressure monitoring (ABPM) values: WCH HS Normal BP OBP (mm Hg)  140 and/or 90  140 and/or 90  140 and/or 90 ABPM (mm Hg)  135 and 85  135 and 85  135 and 85 The patients were divided into two groups: 129 patients with WCH and 121 normotensive patients, and were evaluated after 10 years of follow-up. Glucose blood level, lipid profile and left ventricular mass index (LVMI) were measured. Results Age, gender, smoking habits and glucose blood level were similar at baseline among normotensive patients and patients with white coat hypertension. Yet, BMI, total cholesterol levels, lipid levels and LVMI were significantly greater in white-coat hypertensive patients. Sustained hypertension was developed by 48 patients with WCH and 21 normotensive patients. We found an independent association between WCH and SH at 10 years of follow-up [OR: 2.5 (95% CI 1.2-4.2)]. Conclusion Progression to sustained hypertension was greater in patients with white coat hypertension compared to normotensive patients.  

Metadatos destacados

Colecciones
Argentine Journal of Cardiology

Editor

Sociedad Argentina de Cardiología

Fuente

Revista Argentina de Cardiología; Vol 80, No 3 (2012), Argentine Journal of Cardiology; Vol 80, No 3 (2012)

Citación

Paez, Olga B. et al., “Hipertensión de guardapolvo blanco: evolución a hipertensión sostenida luego de 10 años de seguimiento,” Archivo PPCT, consulta 2 de abril de 2026, http://archivoppct.caicyt.gov.ar/items/show/8101.

Dublin Core

Materia

Autor

Paez, Olga B.
Puleio, Pablo A.
Gorocito, Marta G.
Visser, Miguel
Schiavone, Miguel
Majul, Claudio R.

Fuente

Revista Argentina de Cardiología; Vol 80, No 3 (2012)
Argentine Journal of Cardiology; Vol 80, No 3 (2012)

Editor

Sociedad Argentina de Cardiología

Fecha

2012-05-28

Derechos

Los que firman al pié, certificamos que tenemos total responsabilidad por la conducción de este estudio y por el diseño y la interpretación de los datos. Nosotros escribimos el manuscrito y somos responsables por la decisión acerca del mismo. Cada uno de nosotros cumple la definición de autor como se afirma en el Comité Internacional de Editores de Revistas Médicas (International Committee of Medical Journal Editors, ver www.icmje.org). Nosotros hemos visto y aprobado el manuscrito final. Ni el artículo, ni ninguna parte esencial del mismo, incluido las tablas y las figuras, será publicado o admitido para arbitrar a otra parte antes de aparecer en la Revista.También notificamos haber leído la sección “conflicto de intereses”, y revelaríamos cualquiera que existiera. Dejamos constancia que si nuestro artículo se publicara en la RAC, cederíamos los derechos (copyright) a la Revista.Los documentos publicados en esta revista están bajo la licencia Creative Commons Atribución-NoComercial-Compartir-Igual 2.5 Argentina.
Those signing below certify that we have full responsibility for the conduction of this study and for the design and interpretation of the information. We wrote the manuscript and are responsible for its decision. Each of us fulfills the definition of authorship as stated by the International Committee of Medical Journal Editors ( www.icmje.org). We have signed and approved the final manuscript. Neither the manuscript, nor any essential part thereof, including tables and figures, will be published or accepted for refereeing elsewhere before being published in the Journal. We have also read the "Conflict of Interest" section and would disclose any existing. We state that if our manuscript is published in the RAC, we shall transfer the copyright to the Journal.

Formato

Idioma

spa
eng

Tipo

info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion