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PPCT

hipertensión matinal y comportamiento no dipper en embarazadas con hipertensión de guardapolvo blanco;
Morning Hypertension and Non-dipper Behavior in Pregnant Women with White Coat Syndrome

Creators:Paéz, Olga B., Cervino, Claudio, Puleio, Pablo, Estevez, Ariel, Cragnolino, Román, Visser, Miguel, Mazzeo, Silvina, Majul, Claudio
2015-05-07

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Descripción

Antecedentes: la hipertensión de guardapolvo blanco (HGB) es común en el embarazo pero, su evolución clínica  es aun objeto de debate. Por otro lado, la presión al despertar  elevada (PDE)  y el comportamiento no dipper (CND)  medidos por monitoreo de presión arterial ambulatorio  (MAPA), se asocian a mayor riesgo de eventos cardiovasculares. Sin embargo, han sido poco estudiados en esta población.   Objetivo primario: evaluar  la PDE y el CND en embarazadas  con HGB respecto a un grupo control de normotensas (N).   Objetivo secundario: evaluar si la HGB, la PDE  y el CND  en etapa precoz del embarazo  se relacionan a mayor  hipertensión sostenida (HS) en la segunda mitad del embarazo. Métodos: estudio prospectivo, se incluyeron 198 primigestas en semana 20 de gestación, continuaron en seguimiento 50 con HGB y 45 con N. Se registró laboratorio de rutina, presión de consultorio (PC)  y MAPA en la inclusión y a las 32 semanas de gestación. La PDE  y CND fueron evaluadas por MAPA.   Resultados: Las variables: edad, glucemia, valores de presion por MAPA  diurnos y nocturnos fueron similares en el examen basal en ambos grupos. Por el contrario, las  con HGB presentaron valores significativamente superiores de PDE y CND, los cuales se asociaron en forma independiente con HS en la segunda mitad del embarazo.     Conclusion: Las gestantes con HGB presentaron mayor PDE y CND en semana 20 del embarazo, respecto a N. La evolucion a HS en la segunda mitad de gestacion , fue  mayor respecto a normotensas pero sin  valor estadistico significativo.Antecedentes: la hipertensión de guardapolvo blanco (HGB) es común en el embarazo pero, su evolución clínica  es aun objeto de debate. Por otro lado, la presión al despertar  elevada (PDE)  y el comportamiento no dipper (CND)  medidos por monitoreo de presión arterial ambulatorio  (MAPA), se asocian a mayor riesgo de eventos cardiovasculares. Sin embargo, han sido poco estudiados en esta población.   Objetivo primario: evaluar  la PDE y el CND en embarazadas  con HGB respecto a un grupo control de normotensas (N).   Objetivo secundario: evaluar si la HGB, la PDE  y el CND  en etapa precoz del embarazo  se relacionan a mayor  hipertensión sostenida (HS) en la segunda mitad del embarazo. Métodos: estudio prospectivo, se incluyeron 198 primigestas en semana 20 de gestación, continuaron en seguimiento 50 con HGB y 45 con N. Se registró laboratorio de rutina, presión de consultorio (PC)  y MAPA en la inclusión y a las 32 semanas de gestación. La PDE  y CND fueron evaluadas por MAPA.   Resultados: Las variables: edad, glucemia, valores de presion por MAPA  diurnos y nocturnos fueron similares en el examen basal en ambos grupos. Por el contrario, las  con HGB presentaron valores significativamente superiores de PDE y CND, los cuales se asociaron en forma independiente con HS en la segunda mitad del embarazo.     Conclusion: Las gestantes con HGB presentaron mayor PDE y CND en semana 20 del embarazo, respecto a N. La evolucion a HS en la segunda mitad de gestacion , fue  mayor respecto a normotensas pero sin  valor estadistico significativo.

Background: White coat syndrome (WCS) is common during pregnancy, although little is known about its clinical outcomeduring gestation. Morning hypertension and the non-dipper behavior, measured by ambulatory blood pressure monitoring(ABPM), are associated with greater risk of cardiovascular events. However, there are few studies during pregnancy.Objectives: The primary aim of the study was to evaluate morning hypertension and the non-dipper behavior in pregnantwomen with WCS versus a control normotensive group. A secondary objective was to evaluate whether WCS, morning hypertensionand the non-dipper behavior in the second trimester of pregnancy were associated with greater hypertension inthe third trimester.Methods: This prospective study included 95 primiparae in the 20th week of gestation, 50 with WCS and 45 as normotensivecontrol group. Routine lab tests, office blood pressure and ABPM at inclusion and in the 32th week of gestation were recorded.Morning hypertension and the non-dipper behavior were evaluated by ABPM.Results: Age, and baseline blood glucose level and daytime and nighttime blood pressure by ABPM were similar in both groups.Conversely, patients presenting WCS had significantly higher values of morning hypertension and non-dipper behavior, whichwere independently associated with sustained hypertension in the third trimester of pregnancy.Conclusions: Pregnant women with WCS in the 20th week of gestation presented greater morning hypertension and non-dipperbehavior and progressed more frequently to sustained hypertension than the control normotensive group.

Metadatos destacados

Colecciones
Argentine Journal of Cardiology

Editor

Sociedad Argentina de Cardiología

Fuente

Revista Argentina de Cardiología; Vol 83, No 2 (2015); 107-111, Argentine Journal of Cardiology; Vol 83, No 2 (2015); 107-111

Citación

Paéz, Olga B. et al., “hipertensión matinal y comportamiento no dipper en embarazadas con hipertensión de guardapolvo blanco,” Archivo PPCT, consulta 1 de abril de 2026, http://archivoppct.caicyt.gov.ar/items/show/8653.

Dublin Core

Materia

Autor

Paéz, Olga B.
Cervino, Claudio
Puleio, Pablo
Estevez, Ariel
Cragnolino, Román
Visser, Miguel
Mazzeo, Silvina
Majul, Claudio

Fuente

Revista Argentina de Cardiología; Vol 83, No 2 (2015); 107-111
Argentine Journal of Cardiology; Vol 83, No 2 (2015); 107-111

Editor

Sociedad Argentina de Cardiología

Fecha

2015-05-07

Derechos

Los que firman al pié, certificamos que tenemos total responsabilidad por la conducción de este estudio y por el diseño y la interpretación de los datos. Nosotros escribimos el manuscrito y somos responsables por la decisión acerca del mismo. Cada uno de nosotros cumple la definición de autor como se afirma en el Comité Internacional de Editores de Revistas Médicas (International Committee of Medical Journal Editors, ver www.icmje.org). Nosotros hemos visto y aprobado el manuscrito final. Ni el artículo, ni ninguna parte esencial del mismo, incluido las tablas y las figuras, será publicado o admitido para arbitrar a otra parte antes de aparecer en la Revista.También notificamos haber leído la sección “conflicto de intereses”, y revelaríamos cualquiera que existiera. Dejamos constancia que si nuestro artículo se publicara en la RAC, cederíamos los derechos (copyright) a la Revista.Los documentos publicados en esta revista están bajo la licencia Creative Commons Atribución-NoComercial-Compartir-Igual 2.5 Argentina.
Those signing below certify that we have full responsibility for the conduction of this study and for the design and interpretation of the information. We wrote the manuscript and are responsible for its decision. Each of us fulfills the definition of authorship as stated by the International Committee of Medical Journal Editors ( www.icmje.org). We have signed and approved the final manuscript. Neither the manuscript, nor any essential part thereof, including tables and figures, will be published or accepted for refereeing elsewhere before being published in the Journal. We have also read the "Conflict of Interest" section and would disclose any existing. We state that if our manuscript is published in the RAC, we shall transfer the copyright to the Journal.

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spa
eng

Tipo

info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion