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hipertensión no controlada se asocia a hipotensión postprandial: un estudio con monitoreo domiciliario de la presión arterial - Archivo PPCT

La hipertensión no controlada se asocia a hipotensión postprandial: un estudio con monitoreo domiciliario de la presión arterial;
Uncontrolled Hypertension is Associated with Postprandial Hypotension

Creators:Alfie, José, Barochiner, Jessica, Nuñez, Myriam, Cuffaro, Paula E., Marín, Marcos J., Rada, Marcelo A., Morales, Margarita S., Aparicio, Lucas S., Galarza, Carlos R., Waisman, Gabriel D.
2015-05-07

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Descripción

Resumen Introducción En un estudio previo que incorporó mediciones post almuerzo al esquema convencional  de monitoreo domiciliario de presión arterial, hemos detectado hipotensión postprandial  en » ¼ de nuestros pacientes hipertensos. Objetivos En el presente estudio comparamos el cambio postprandial de la presión arterial sistólica, y la correspondiente respuesta cronotrópica, en relación al control de la hipertensión. Material y métodos Evaluamos prospectivamente con monitoreo domiciliario de presión arterial a 140 hipertensos tratados mayores de 40 años. El control de la hipertensión se basó en el promedio de presión arterial matinal y vespertina, tomando como valor de corte 135/85 mmHg. Se consideró hipotensión postprandial cuando la presión arterial sistólica disminuyó 20 mmHg ó más respecto del valor preprandial en al menos 1 de 3 almuerzos. Resultados Detectamos hipotensión postprandial, en el 13,2% (n = 10) de los hipertensos controlados y en el 42,2% (n = 27) de los no controlados (P&lt; 0,001). Después de los almuerzos la presión arterial sistólica disminuyó en promedio 9,5±10,5 mmHg (6,4±7,8%) en los hipertensos no controlados y 3,2±7,8 mmHg (2,6±6,5 %) en los controlados (p &lt; 0,001), sin diferencia significativa en la respuesta crontrópica.  El análisis de regresión lineal múltiple, confirmó que el delta postprandial de presión arterial sistólica se asoció significativamente con el control de la hipertensión (Beta = -0,26; P = 0,002) pero no con la edad. Al estratificar a los pacientes por el control de la hipertensión, se observó que la respuesta postprandial de la frecuencia cardíaca y de la presión arterial sistólica correlacionaron entre sí de manera inversa en los controlados (r = -0,42; P &lt; 0,001), sin relación significativa en los no controlados. Conclusión La falta de control de la hipertensión se asoció a una anormal respuesta circulatoria postprandial que predispone a la hipotensión.

Background: In a previous study that incorporated post-lunch measurements to the conventional scheme of home-based bloodpressure monitoring, we detected postprandial hypotension in about a quarter of hypertensive patients. The coexistence ofhypertension with hypotension poses a therapeutic dilemma, suggesting that the control of hypertension might attenuatepostprandial hypotension.Objectives: The aim of this study was to compare the postprandial change of systolic blood pressure, and the correspondingchronotropic response, associated to the control of hypertension.Methods: We prospectively evaluated 140 treated hypertensive patients, aged over 40 years, with home-based blood pressuremonitoring. The control of hypertension was based on the average morning and evening blood pressure, considering 135/85mmHg as cutoff value. Postprandial hypotension was defined as a drop in systolic blood pressure equal to or greater than 20mmHg with respect to the preprandial value in at least one of three lunches.Results: Postprandial hypotension was found in 13.2% (n=10) of patients with controlled hypertension and in 42.2% (n=27)with uncontrolled hypertension (p&lt;0.001). After lunch, the average decrease of systolic blood pressure was 9.5±10.5 mmHg(6.4%±7.8%) in patients with uncontrolled hypertension and 3.2±7.8 mmHg (2.6%±6.5%) in those with controlled hypertension(p&lt;0.001), with no significant difference in the chronotropic response. After stratifying the patients by hypertension control, the postprandial response of heart rate and systolic blood pressure showed a significant inverse correlation in controlledhypertensive patients (r=-0.24; p=0.035), and a not significant correlation in uncontrolled patients. On the multiplelinear regression analysis, lack of blood pressure control (beta=0.26, p=0.002) and female gender (beta=0.22; p&lt;0.001) weresignificant predictors of a postprandial drop in systolic blood pressure, without a significant influence of age or number ofantihypertensive drugs.Conclusion: Lack of blood pressure control was associated with an abnormal postprandial circulatory response that predisposesto hypotension.

Metadatos destacados

Colecciones
Argentine Journal of Cardiology

Editor

Sociedad Argentina de Cardiología

Fuente

Revista Argentina de Cardiología; Vol 83, No 2 (2015); 119-123, Argentine Journal of Cardiology; Vol 83, No 2 (2015); 119-123

Citación

Alfie, José et al., “La hipertensión no controlada se asocia a hipotensión postprandial: un estudio con monitoreo domiciliario de la presión arterial,” Archivo PPCT, consulta 4 de abril de 2026, http://archivoppct.caicyt.gov.ar/items/show/8665.

Dublin Core

Materia

Autor

Alfie, José
Barochiner, Jessica
Nuñez, Myriam
Cuffaro, Paula E.
Marín, Marcos J.
Rada, Marcelo A.
Morales, Margarita S.
Aparicio, Lucas S.
Galarza, Carlos R.
Waisman, Gabriel D.

Fuente

Revista Argentina de Cardiología; Vol 83, No 2 (2015); 119-123
Argentine Journal of Cardiology; Vol 83, No 2 (2015); 119-123

Editor

Sociedad Argentina de Cardiología

Fecha

2015-05-07

Derechos

Los que firman al pié, certificamos que tenemos total responsabilidad por la conducción de este estudio y por el diseño y la interpretación de los datos. Nosotros escribimos el manuscrito y somos responsables por la decisión acerca del mismo. Cada uno de nosotros cumple la definición de autor como se afirma en el Comité Internacional de Editores de Revistas Médicas (International Committee of Medical Journal Editors, ver www.icmje.org). Nosotros hemos visto y aprobado el manuscrito final. Ni el artículo, ni ninguna parte esencial del mismo, incluido las tablas y las figuras, será publicado o admitido para arbitrar a otra parte antes de aparecer en la Revista.También notificamos haber leído la sección “conflicto de intereses”, y revelaríamos cualquiera que existiera. Dejamos constancia que si nuestro artículo se publicara en la RAC, cederíamos los derechos (copyright) a la Revista.Los documentos publicados en esta revista están bajo la licencia Creative Commons Atribución-NoComercial-Compartir-Igual 2.5 Argentina.
Those signing below certify that we have full responsibility for the conduction of this study and for the design and interpretation of the information. We wrote the manuscript and are responsible for its decision. Each of us fulfills the definition of authorship as stated by the International Committee of Medical Journal Editors ( www.icmje.org). We have signed and approved the final manuscript. Neither the manuscript, nor any essential part thereof, including tables and figures, will be published or accepted for refereeing elsewhere before being published in the Journal. We have also read the "Conflict of Interest" section and would disclose any existing. We state that if our manuscript is published in the RAC, we shall transfer the copyright to the Journal.

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spa
eng

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info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion