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Selección Genómica

Creators:Cantet, R. J.C.; Departamento de Producción Animal, Facultad de Agronomía, UBA
Consejo Nacional de Investigaciones Científicas y Técnicas, Gualdrón Duarte, J. L.; Departamento de Producción Animal, Facultad de Agronomía, UBA
Consejo Nacional de Investigaciones Científicas y Técnicas, Munilla Leguizamón, S.; Departamento de Producción Animal, Facultad de Agronomía, UBA
Consejo Nacional de Investigaciones Científicas y Técnicas
2013-11-28

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Descripción

La evaluación genética animal tiene como objeto la predicción del mérito genético individual o valor de cría (en inglés, breeding value, BV). En el modelo clásico de la genética cuantitativa, los BVs de los caracteres de importancia económica son  controlados por un número muy grande (más formalmente, tendiendo a infinito) de genes: el modelo infinitesimal. Estos genes actúan en forma aditiva sin ligamiento entre ellos, cada uno con un efecto pequeño sobre la expresión fenotípica del carácter (Bulmer, 1985). En consecuencia, y hasta hoy, la selección en animales se realizó asumiendo una distribución normal para el BV resultante de una suma que tiende a infinito de variables aleatorias cada una de valor muy pequeño. En la actualidad cada uno de los genes o fracciones del genoma que afectan los caracteres productivos bajo un modelo infinitesimal es conocido como QTL (en inglés Quantitative Trait Locus). Si bien grande, el máximo número de genes en un genoma como por ejemplo el humano, se estima en el rango entre 20.000 a 25.000 (International Human Consortium, 2004), ciertamente un número finito. Los avances en genética molecular han mostrado que las características cuantitativas están afectadas por unos pocos genes con gran impacto y muchos con escaso, de modo tal que la distribución del efecto de los QTLs es aproximadamente exponencial (Otto y Jones, 2000)

Metadatos destacados

Colecciones
Revista Argentina de Producción Animal

Editor

Asociación Argentina de Producción Animal

Fuente

Revista Argentina de Producción Animal; Vol 28, No 2 (2008): mayo - agosto 2008; 133-136

Citación

Cantet, R. J.C.; Departamento de Producción Animal, Facultad de Agronomía, UBA Consejo Nacional de Investigaciones Científicas y Técnicas, Gualdrón Duarte, J. L.; Departamento de Producción Animal, Facultad de Agronomía, UBA Consejo Nacional de Investigaciones Científicas y Técnicas, y Munilla Leguizamón, S.; Departamento de Producción Animal, Facultad de Agronomía, UBA Consejo Nacional de Investigaciones Científicas y Técnicas, “Selección Genómica,” Archivo PPCT, consulta 2 de abril de 2026, http://archivoppct.caicyt.gov.ar/items/show/8815.

Dublin Core

Materia

Autor

Cantet, R. J.C.; Departamento de Producción Animal, Facultad de Agronomía, UBA
Consejo Nacional de Investigaciones Científicas y Técnicas
Gualdrón Duarte, J. L.; Departamento de Producción Animal, Facultad de Agronomía, UBA
Consejo Nacional de Investigaciones Científicas y Técnicas
Munilla Leguizamón, S.; Departamento de Producción Animal, Facultad de Agronomía, UBA
Consejo Nacional de Investigaciones Científicas y Técnicas

Fuente

Revista Argentina de Producción Animal; Vol 28, No 2 (2008): mayo - agosto 2008; 133-136

Editor

Asociación Argentina de Producción Animal

Fecha

2013-11-28

Formato

Idioma

spa

Tipo

info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion