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en mujeres - Archivo PPCT

Resultados a corto plazo de la cirugía coronaria aislada o combinada en mujeres;
Short-Term Outcomes of Isolated and Combined Coronary Artery Bypass Graft Surgery in Women

Creators:Giorgini, Julio C., Rubio, Miguel, Baldi, Julio, David, Michel, Higa, Claudio, Borracci, Raúl A., Tenorio Nuñez, Osvaldo M.
2020-11-27

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Descripción

Introducción: En relación con la cirugía coronaria, existen discrepancias respecto del pronóstico y tratamiento de la enfermedadcardiovascular en la mujer entre distintos estudios internacionales.Objetivo: Analizar los resultados de mortalidad y complicaciones hospitalarias y a 60 días luego de la cirugía de revascularizaciónmiocárdica aislada o combinada, en forma comparativa entre mujeres y varones.Material y métodos: Se analizaron en forma retrospectiva los resultados hospitalarios y a 60 días de la cirugía de revascularizacióncoronaria aislada o combinada de acuerdo con el sexo, operados entre 2011 y 2017. Se compararon las variablesperioperatorias, la mortalidad esperada con el EuroSCORE II y la mortalidad observada por toda causa. Se realizó un análisisde propensión para equiparar las poblaciones de mujeres y varones.Resultados: De 1670 cirugías de revascularización coronaria aisladas o combinadas, el 27,4% (n: 457) eran mujeres; y, de 1305cirugías aisladas, el 14,2% (n: 185) eran mujeres. La mortalidad en las mujeres a 30 y 60 días fue del 2,7% y del 4,3% vs. el2,1% (RR = 1,26 IC95% 0,49-3,26, p = 0,632) y el 2,3% (RR = 1,86 IC95% 0,86-4,05, p = 0,113, potencia 53%) en los varones.Tras el análisis de propensión de los pacientes sometidos a cirugía coronaria asilada, la mortalidad a 60 días en las mujeresfue del 4,0% vs. 2,3% en los varones (RR = 1,75 IC95% 0,52-5,87, p = 0,359).Conclusiones: En comparación con los varones, las mujeres sometidas a cirugía de revascularización coronaria tuvieron másedad y mayor riesgo esperado por el EuroSCORE II, peor función renal tanto para la cirugía coronaria combinada como aislada.La mortalidad luego de la cirugía de revascularización coronaria aislada o combinada fue mayor en mujeres que en hombresa 60 días e, incluso, esta diferencia se mantuvo después de ajustar por confundidores.

Background: The outcome and treatment of cardiovascular disease in women differ among international studies.Objective: The aim of this study was to compare in-hospital mortality and complications with mortality and complications at60 days following isolated or combined coronary artery bypass graft surgery between women and men.Methods: The outcomes during hospitalization and at 60 days following isolated or combined coronary artery bypass graftsurgery procedures performed between 2011 and 2017 were retrospectively analyzed. Perioperative variables, expected allcausemortality estimated by EuroSCORE II and observed all-cause mortality were compared. A propensity score analysiswas performed to match female and male populations.Results: Of the 1670 isolated or combined coronary artery bypass graft procedures, 27.4% (n=457) were performed in women,and 185 (14.2%) of 1305 isolated surgeries corresponded to women. Mortality in women at 30 and 60 days was 2.7% and 4.3%.respectively, vs. 2.1% (RR: 1.26; 95% CI, 0.49-3.26; p=0.632) and 2.3% (RR: 1.86; 95% CI, 0.86-4.05, p=0.113, power 53%),respectively, in men. After analyzing the propensity score of patients undergoing isolated revascularization procedures, 60-day mortality in women was 4.0% vs. 2.3% in men (RR: 1.75; 95% CI; 0.52-5.87, p=0.359).Conclusions: Compared with men, women undergoing isolated or combined coronary artery bypass graft surgery were olderand had higher expected risk calculated by EuroSCORE II and worse renal function. Mortality after isolated or combinedcoronary artery bypass graft surgery was higher in women than in men at 60 days, and this difference remained even afteradjusting for confounders.

Metadatos destacados

Colecciones
Argentine Journal of Cardiology

Editor

Sociedad Argentina de Cardiología

Fuente

Revista Argentina de Cardiología; Vol 88, No 5 (2020); 448-453, Argentine Journal of Cardiology; Vol 88, No 5 (2020); 448-453

Citación

Giorgini, Julio C. et al., “Resultados a corto plazo de la cirugía coronaria aislada o combinada en mujeres,” Archivo PPCT, consulta 2 de abril de 2026, http://archivoppct.caicyt.gov.ar/items/show/9751.

Dublin Core

Materia

Autor

Giorgini, Julio C.
Rubio, Miguel
Baldi, Julio
David, Michel
Higa, Claudio
Borracci, Raúl A.
Tenorio Nuñez, Osvaldo M.

Fuente

Revista Argentina de Cardiología; Vol 88, No 5 (2020); 448-453
Argentine Journal of Cardiology; Vol 88, No 5 (2020); 448-453

Editor

Sociedad Argentina de Cardiología

Fecha

2020-11-27

Derechos

Los que firman al pié, certificamos que tenemos total responsabilidad por la conducción de este estudio y por el diseño y la interpretación de los datos. Nosotros escribimos el manuscrito y somos responsables por la decisión acerca del mismo. Cada uno de nosotros cumple la definición de autor como se afirma en el Comité Internacional de Editores de Revistas Médicas (International Committee of Medical Journal Editors, ver www.icmje.org). Nosotros hemos visto y aprobado el manuscrito final. Ni el artículo, ni ninguna parte esencial del mismo, incluido las tablas y las figuras, será publicado o admitido para arbitrar a otra parte antes de aparecer en la Revista.También notificamos haber leído la sección “conflicto de intereses”, y revelaríamos cualquiera que existiera. Dejamos constancia que si nuestro artículo se publicara en la RAC, cederíamos los derechos (copyright) a la Revista.Los documentos publicados en esta revista están bajo la licencia Creative Commons Atribución-NoComercial-Compartir-Igual 2.5 Argentina.
Those signing below certify that we have full responsibility for the conduction of this study and for the design and interpretation of the information. We wrote the manuscript and are responsible for its decision. Each of us fulfills the definition of authorship as stated by the International Committee of Medical Journal Editors ( www.icmje.org). We have signed and approved the final manuscript. Neither the manuscript, nor any essential part thereof, including tables and figures, will be published or accepted for refereeing elsewhere before being published in the Journal. We have also read the "Conflict of Interest" section and would disclose any existing. We state that if our manuscript is published in the RAC, we shall transfer the copyright to the Journal.

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eng
spa

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info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion