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0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f 0000000000 65535 f trailer <]>> startxref 116 %%EOF Angioplastia coronaria en pacientes octogenarios: resultados alejados y predictores de mal pronóstico - Archivo PPCT

Angioplastia coronaria en pacientes octogenarios: resultados alejados y predictores de mal pronóstico;
Percutaneous Coronary Intervention in Octogenarian Patients. Long-term Results and Predictors of Poor Outcome

Creators:Leite Vincenti, Fernando, Seropian, Ignacio M.; Hospital Italiano de Buenos Aires, Portaluppi, Rafael, Cohen, Fernando, Rojas Matas, Carlos A., Fernández, Alejandro D., Agatiello, Carla R., Berrocal, Daniel H.
2018-06-26

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Descripción

INTRODUCCION: La angioplastia coronaria en octogenarios aumenta, pero esta población está poco representada en los estudios randomizados por su alto riesgo. OBJETIVOS: Evaluar los resultados de angioplastia coronaria de pacientes octogenarios e identificar predictores independientes de mala evolución en el seguimiento.MÉTODOS: Estudio retrospectivo, pacientes consecutivos con angioplastia coronaria Junio 2011 a Septiembre 2013 en un Hospital Polivalente. Se compararon octogenarios (edad≥80 años) del resto. Se evaluaron características basales y del procedimiento. Se evaluó mortalidad y los eventos cardiovasculares mayores (MACE, muerte infarto o stroke) a 30 días, 1 y 3 años. Se realizó análisis univariado y multivariado para predictores de mala evolución. RESULTADOS: Se incluyeron 1030 pacientes, 20.2% octogenarios. Edad de octogenarios: 83 años (RIC 81-86). Los octogenarios presentaron más factores de riesgo y comorbilidades. La tasa de éxito y la cantidad de stents fue similar entre los grupos. La tasa de MACE fue mayor en octogenarios a 30 días (14.4% v 4.9%; p&lt;0,001), 1 año (23.9%  vs  8.5%; p&lt;0,001) y a 3 años (p&lt;0.0001), a expensas de mortalidad sin diferencias en los otros puntos, ni en complicaciones del procedimiento. Los predictores independientes de muerte en octogenarios incluyen IRC, EPOC y deterioro de la función ventricular. La edad≥80 años fue un predictor independiente de MACE en la población general. CONCLUSIONES: Observamos una aceptable tasa de éxito de ATC en pacientes octogenarios, asociado a aumento de la mortalidad inmediata y alejada que no parece relacionada con el procedimiento. La IRC, el EPOC y el deterioro de la función ventricular son predictores independientes de mal pronóstico en estos pacientes.

Background: Coronary percutaneous intervention in octogenarian patients is growing due to the rise in life expectancy. However, this population is underrepresented in randomized trials due to its high risk. Objectives: The aim of this study was to evaluate short and long-term outcomes of coronary percutaneous intervention in octogenarian patients, and to identify independent predictors of adverse outcome. Methods: This was a retrospective study including consecutive patients undergoing percutaneous coronary intervention at a general hospital from June 2011 to September 2013. Octogenarian patients (age ≥80 years) were compared with younger patients. Medical history, procedure characteristics and clinical outcomes were evaluated. Major adverse cardiovascular events (MACE consisting of death, myocardial infarction or stroke) were evaluated at 1 month, and 1 and 3 years. Multivariate analysis was performed to assess independent predictors of adverse outcome. Results: A total of 1,030 patients (20.2% octogenarians) were included in the study. Mean age of octogenarian patients was 83 years (IQR 81-86). This population had more cardiovascular risk factors and comorbidities. No differences were observed in procedure success and number of implanted stents. The rate of MACE was significantly higher in octogenarian patients at 1 month (14.4% vs. 4.9%; p&lt;0.001), 1 year (23.9% vs. 8.5%; p&lt;0.001) and 3 years (p&lt;0.0001), due to increased mortality, without differences in myocardial infarction (4.8% vs. 3.8%), stroke (1.7% vs. 1.6%), or procedural complications. Independent predictors of mortality in octogenarian patients were kidney failure, chronic obstructive pulmonary disease and ventricular dysfunction. Age ≥80 years was an independent predictor of MACE in the overall population. Conclusions: Technical success was acceptable in octogenarian patients undergoing percutaneous coronary intervention, but octogenarian patients showed increased early and long-term mortality that appears to be independent of the procedure. Kidney failure, chronic obstructive pulmonary disease and ventricular function impairment were independent predictors of adverse outcome in these patients.

Metadatos destacados

Colecciones
Argentine Journal of Cardiology

Editor

Sociedad Argentina de Cardiología

Fuente

Revista Argentina de Cardiología; Vol 86, No 2 (2018); 110-115, Argentine Journal of Cardiology; Vol 86, No 2 (2018); 110-115

Citación

Leite Vincenti, Fernando et al., “Angioplastia coronaria en pacientes octogenarios: resultados alejados y predictores de mal pronóstico,” Archivo PPCT, consulta 4 de abril de 2026, http://archivoppct.caicyt.gov.ar/items/show/9415.

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Materia

Autor

Leite Vincenti, Fernando
Seropian, Ignacio M.; Hospital Italiano de Buenos Aires
Portaluppi, Rafael
Cohen, Fernando
Rojas Matas, Carlos A.
Fernández, Alejandro D.
Agatiello, Carla R.
Berrocal, Daniel H.

Fuente

Revista Argentina de Cardiología; Vol 86, No 2 (2018); 110-115
Argentine Journal of Cardiology; Vol 86, No 2 (2018); 110-115

Editor

Sociedad Argentina de Cardiología

Fecha

2018-06-26

Derechos

Los que firman al pié, certificamos que tenemos total responsabilidad por la conducción de este estudio y por el diseño y la interpretación de los datos. Nosotros escribimos el manuscrito y somos responsables por la decisión acerca del mismo. Cada uno de nosotros cumple la definición de autor como se afirma en el Comité Internacional de Editores de Revistas Médicas (International Committee of Medical Journal Editors, ver www.icmje.org). Nosotros hemos visto y aprobado el manuscrito final. Ni el artículo, ni ninguna parte esencial del mismo, incluido las tablas y las figuras, será publicado o admitido para arbitrar a otra parte antes de aparecer en la Revista.También notificamos haber leído la sección “conflicto de intereses”, y revelaríamos cualquiera que existiera. Dejamos constancia que si nuestro artículo se publicara en la RAC, cederíamos los derechos (copyright) a la Revista.Los documentos publicados en esta revista están bajo la licencia Creative Commons Atribución-NoComercial-Compartir-Igual 2.5 Argentina.
Those signing below certify that we have full responsibility for the conduction of this study and for the design and interpretation of the information. We wrote the manuscript and are responsible for its decision. Each of us fulfills the definition of authorship as stated by the International Committee of Medical Journal Editors ( www.icmje.org). We have signed and approved the final manuscript. Neither the manuscript, nor any essential part thereof, including tables and figures, will be published or accepted for refereeing elsewhere before being published in the Journal. We have also read the "Conflict of Interest" section and would disclose any existing. We state that if our manuscript is published in the RAC, we shall transfer the copyright to the Journal.

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spa
eng

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info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion